Symbol Name ID |
Thbd
thrombomodulin MGI:98736 |
Darker colors indicate more annotations |
Human Phenotypes | Anti-citrullinated protein antibody positivity |
Rheumatoid factor positive |
Asthma |
Disease(s) Associated with THBD | |||
asthma | |||
rheumatoid arthritis |
Mouse Phenotypes | abnormal leukocyte adhesion |
increased spleen weight |
abnormal spleen morphology |
abnormal leukocyte physiology |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-6 level |
increased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
increased circulating tumor necrosis factor level |
abnormal acute phase protein level |
decreased tumor necrosis factor secretion |
increased susceptibility to endotoxin shock |
decreased susceptibility to bacterial infection |
decreased susceptibility to bacterial infection induced morbidity/mortality |
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Availability | Mouse Genotype | ||||||||||||||
Thbdtm1Wlr/Thbdtm1Wlr | |||||||||||||||
Thbdtm2.1Emc/Thbdtm2.1Emc | |||||||||||||||
Thbdtm2Emc/Thbdtm2Emc | |||||||||||||||
Thbdtm1Wlr/Thbdtm2Rdr | |||||||||||||||
Thbdtm1.1Hlwu/Thbdtm1.1Hlwu Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Tg(Tek-cre)1Ywa/0 Thbdtm2Rdr/Thbdtm2Wlr (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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